1- C -phosphonomethyl- and 1-C-difluorophosphonomethyl-1,4-imino- l -arabinitols as Gal f transferase inhibitors: A comparison University of Alberta | Publication | 2018-05-01 | Chloé Cocaud, Ruixiang B Zheng, Todd L. Lowary, Thomas Poisson, Xavier Pannecoucke, Cyril Nicolas, Olivier R Martin |
A Convergent Route to Enantiomers of the Bicyclic Monosaccharide Bradyrhizose Leads to Insight into the Bioactivity of an Immunologically Silent Lipopolysaccharide GlycoNet, University of Alberta | Publication | 2018-12-01 | Claude Larrivee Aboussafy, Lotte Bettina Andersen Gersby, Antonio Molinaro, Mari-Anne Newman, Todd L. Lowary |
A novel sensitive immunoassay targeting the MTX -Lipoarabinomannan epitope meets the WHO\textquotesingles performance target for Tuberculosis diagnosis University of Alberta | Publication | 2018-09-01 | George B Sigal, Abraham Pinter, Todd L. Lowary, Masanori Kawasaki, Andra Li, Anu Mathew, Michael Tsionsky, Ruixiang Blake Zheng, Tatiana Plisova, Ke Shen, Kiyonori Katsuragi, Alok Choudhary, William J Honnen, Payam Nahid, Claudia M Denkinger, Tobias Broger |
A Route to Polyprenol Pyrophosphate-Based Probes of O-Polysaccharide Biosynthesis in Klebsiella pneumoniae O2a University of Alberta | Publication | 2019-01-01 | Ryan Sweeney, Todd L. Lowary |
An Oxidation-Amidation Approach for the Synthesis of Glycuronamides University of Alberta | Publication | 2016-05-01 | Sicheng Lin, Roger A. Ashmus, Todd L. Lowary |
Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction University of Alberta | Publication | 2016-04-01 | Tingting Chen, Caroline Blanc, Anke Z. Eder, Rafael Prados-Rosales, Ana Camila Oliveira Souza, Ryung S. Kim, Aharona Glatman-Freedman, Maju Joe, Yu Bai, Todd L. Lowary, Rachel Tanner, Michael J. Brennan, Helen A. Fletcher, Helen McShane, Arturo Casadevall, Jacqueline M. Achkar |
Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO (H) blood group A and B glycosyltransferases University of Alberta | Publication | 2018-06-01 | Susannah M L Gagnon, Max S G Legg, Robert Polakowski, James A Letts, Mattias Persson, Shuangjun Lin, Ruixiang Zheng, Brian Rempel, Brock Schuman, Omid Haji-Ghassemi, Svetlana N Borisova, Monica M Palcic, Stephen V Evans |
De Novo Asymmetric Synthesis of a 6-O-Methyl-d-glycero-l-gluco-heptopyranose-Derived Thioglycoside for the Preparation of Campylobacter jejuni NCTC 11168 Capsular Polysaccharide Fragments University of Alberta | Publication | 2016-03-01 | Roger Ashmus, Anushka B Jayasuriya, Ying-Jie Lim, George A O'Doherty, Todd L. Lowary |
Detection of lipoarabinomannan in urine and serum of HIV -positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry University of Alberta | Publication | 2018-07-01 | Anita G Amin, Prithwiraj De, John S Spencer, Patrick J Brennan, Joshua Daum, Barbara G Andre, Maju Joe, Yu Bai, Lars Laurentius, Marc D Porter, William J Honnen, Alok Choudhary, Todd L. Lowary, Abraham Pinter, Delphi Chatterjee |
Development of an Orthogonal Protection Strategy for the Synthesis of Mycobacterial Arabinomannan Fragments University of Alberta | Publication | 2015-11-01 | Kamar Sahloul, Todd L. Lowary |
Galactofuranose inMycoplasma mycoidesis important for membrane integrity and conceals adhesins but does not contribute to serum resistance University of Alberta | Publication | 2015-10-01 | Elise Schieck, Carole Lartigue, Joachim Frey, Nicolas Vozza, Jan Hegermann, Rachel A. Miller, Ezequiel Valguarnera, Cecilia Muriuki, Jochen Meens, Vish Nene, Jan Naessens, Johann Weber, Todd L. Lowary, Sanjay Vashee, Mario F. Feldman, Joerg Jores |
Identification of a Novel Mycobacterial Arabinosyltransferase Activity Which Adds an Arabinosyl Residue to $\upalpha$-d-Mannosyl Residues University of Alberta | Publication | 2016-04-01 | Shiva kumar Angala, Michael R. McNeil, Lu Zou, Avraham Liav, Junfeng Zhang, Todd L. Lowary, Mary Jackson |
Insights into mycobacteria interactions with the host innate immune system from a novel array of synthetic mycobacterial glycans University of Alberta | Publication | 2017-10-01 | Ruixiang Blake Zheng, Sabine A. F. Jé gouzo, Maju Joe, Yu Bai, Huu-Anh Tran, Ke Shen, Jörn Saupe, Li Xia, Md. Faiaz Ahmed, Yu-Hsuan Liu, Pratap Subhashrao Patil, Ashish Tripathi, Shang-Cheng Hung, Maureen E. Taylor, Todd L. Lowary, Kurt Drickamer |
Klebsiella pneumoniae O1 and O2ac antigens provide prototypes for an unusual strategy for polysaccharide antigen diversification University of Alberta, University of Guelph | Publication | 2019-05-01 | Steven D Kelly, Bradley R Clarke, Olga Ovchinnikova, Ryan Sweeney, Monica L Williamson, Todd L. Lowary, Christopher Whitfield |
Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan inMycobacterium tuberculosis University of Alberta | Publication | 2016-08-01 | James Harrison, Georgina Lloyd, Maju Joe, Todd L. Lowary, Edward Reynolds, Hannah Walters-Morgan, Apoorva Bhatt, Andrew Lovering, Gurdyal S. Besra, Luke J. Alderwick |
Molecular basis for structural diversity in serogroup O2-antigen polysaccharides inKlebsiella pneumoniae University of Alberta, University of Guelph | Publication | 2018-02-01 | Bradley R Clarke, Olga Ovchinnikova, Steven D Kelly, Monica L Williamson, Jennifer E Butler, Bin Liu, Lu Wang, Xi Guo, Rainer Follador, Todd L. Lowary, Christopher Whitfield |
Partnering Teachers and Scientists: Translating Carbohydrate Research into Curriculum Resources for Secondary Science Classrooms | Publication | 2019-03-01 | Ryan Snitynsky, Kerry Rose, Jerine M Pegg |
Stereocontrolled synthesis of $\upalpha$-xylofuranosides using a conformationally-restricted donor University of Alberta | Publication | 2018-06-01 | Li Zhang, Ke Shen, Hashem A Taha, Todd L. Lowary |
Stereocontrolled Synthesis of 2-Deoxy-galactopyranosides via Isopropylidene-Protected 6-O-Silylated Donors University of Alberta | Publication | 2018-03-27 | Dan-Mei Yang, Yue Chen, Ryan Sweeney, Todd L. Lowary, Xing-Yong Liang |
Synthesis and Evaluation of Bicyclo[3.1.0]hexane-Based UDP -Galf Analogues as Inhibitors of the Mycobacterial Galactofuranosyltransferase GlfT2 University of Alberta | Publication | 2016-08-01 | Todd L. Lowary, Jing Li |
Synthesis of a homologous series of galactofuranose-containing mycobacterial arabinogalactan fragments University of Alberta | Publication | 2016-11-01 | Maju Joe, Todd L. Lowary |
Synthesis of the Campylobacter jejuni 81-176 strain capsular polysaccharide repeating unit reveals the absolute configuration of its O-methyl phosphoramidate motif University of Alberta | Publication | 2018-10-01 | Narasimharao Thota, Michael J Ferguson, Ryan Sweeney, Todd L. Lowary |
Synthesis of the highly branched hexasaccharide core of chlorella virus N-linked glycans University of Alberta | Publication | 2018-10-01 | Sicheng Lin, Todd L. Lowary |
Synthetic polyprenol-pyrophosphate linked oligosaccharides are efficient substrates for mycobacterial galactan biosynthetic enzymes University of Alberta | Publication | 2018-02-20 | Xiaochao Xue, Ruixiang Zheng, Akihiko Koizumi, Ling Han, John Klassen, Todd L. Lowary |
The LPG 1x family from Leishmania major is constituted of rare eukaryotic galactofuranosyltransferases with unprecedented catalytic properties University of Alberta | Publication | 2018-12-01 | Jihen Ati, Cyril Colas, Pierre Lafite, Ryan Sweeney, Ruixiang Zheng, Todd L. Lowary, Richard Daniellou |
The N-glycan structures of the antigenic variants of chlorovirus PBCV -1 major capsid protein help to identify the virus-encoded glycosyltransferases University of Alberta | Publication | 2019-02-01 | Immacolata Speciale, Garry A Duncan, Luca Unione, Irina V Agarkova, Domenico Garozzo, Jesú s Jiménez-Barbero, Sicheng Lin, Todd L. Lowary, Antonio Molinaro, Eric Noel, Maria Elena Laugieri, Michela G Tonetti, James L Van Etten, Cristina De Castro |
The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the $\upalpha$(1 $\rightarrow$ 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis University of Alberta | Publication | 2018-06-01 | Monika Jankute, Luke J Alderwick, Alice R Moorey, Maju Joe, Sudagar S Gurcha, Lothar Eggeling, Todd L. Lowary, Anne Dell, Poh-Choo Pang, Tiandi Yang, Stuart Haslam, Gurdyal S Besra |
Triazole-Linked Iminosugars and Aromatic Systems as Simplified UDP -Galf Mimics: Synthesis and Preliminary Evaluation as Galf -Transferase Inhibitors University of Alberta | Publication | 2017-11-01 | Chloé Cocaud, Audrey Maujoin, Ruixiang B. Zheng, Todd L. Lowary, Nuno Rodrigues, Nathalie Percina, Agnes Chartier, Frédéric Buron, Sylvain Routier, Cyril Nicolas, Olivier R. Martin |
Studies on the Synthesis of Bacterial Glycans | Publication | 2017-04-10 | Lei Wang |
Bifunctional galactosyltransferase activities are required for the biosynthesis of the Klebsiella pneumoniae O2 polysaccharide University of Alberta, University of Guelph | Presentation | 2016-06-19 | "Clarke, B.R.", "Williamson, M.", Olga Ovchinnikova, Ryan Sweeney, Todd L. Lowary, Christopher Whitfield |
A bifunctional galactosyltransferase required for polymerization of the Klebsiella pneumoniae O2a polysaccharide contains a novel galactofuranosyltransferase domain University of Alberta, University of Guelph | Presentation | 2018-06-18 | "Bradley R. Clarke", Olga Ovchinnikova, "Evan Mallette", Ryan Sweeney, Todd L. Lowary, Matthew S. Kimber, Christopher Whitfield |
A multifunctional protein acts as a polymerase, chain terminator and chain-length regulator in the biosynthesis of lipopolysaccharide O-antigen in Klebsiella pneumoniae O12 University of Guelph, University of Alberta | Presentation | 2017-06-20 | "Williams, D.M.", Olga Ovchinnikova, "Koizumi, A.", Matthew S. Kimber, Todd L. Lowary, Christopher Whitfield |
A multifunctional protein acts as a polymerase, chain terminator and chain-length regulator in the biosynthesis of lipopolysaccharide O-antigen in Klebsiella pneumoniae O12 University of Alberta, University of Guelph | Presentation | 2016-06-12 | "Williams, D.M.", Olga Ovchinnikova, Iain Mainprize, "Koizumi, A.", Todd L. Lowary, Christopher Whitfield |
A multifunctional protein acts as a polymerase, chain terminator and chain-length regulator in the biosynthesis of lipopolysaccharide O-antigen in Klebsiella pneumoniae O12 University of Alberta, University of Guelph | Presentation | 2016-06-19 | "Williams, D.M.", "Ovc", Iain Mainprize, "Koizumi, A.", Todd L. Lowary, Christopher Whitfield |
Characterization of the genetic components responsible for Klebsiella pneumoniae terminal modifications of the O2a polysaccharide antigen University of Alberta | Presentation | 2018-06-18 | "Stephen D. Kelly", "Bradley R. Clarke", Olga Ovchinnikova, Ryan Sweeney, Todd L. Lowary, "whit" |
Glycosyltransferases that generate diversity in the Klebsiella pneumoniae galactan O-polysaccharides University of Alberta, University of Guelph | Presentation | 2016-06-19 | "Williamson, M.", "Clarke, B.R.", Olga Ovchinnikova, Ryan Sweeney, Todd L. Lowary, Christopher Whitfield |
Multiple genetic loci are associated with serotype diversity among Klebsiella pneumoniae galactan O antigens University of Alberta, University of Guelph | Presentation | 2017-06-20 | "Clarke, B.R.", "Butler, J", Olga Ovchinnikova, "Kelly, S.", "Williamson, M.", Ryan Sweeney, Todd L. Lowary, Christopher Whitfield |
New insights into lipopolysaccharide assembly and export University of Alberta | Publication | 2019-12-01 | Ryan Sweeney, Todd L. Lowary |
Twenty Years of Mycobacterial Glycans: Furanosides and Beyond University of Alberta | Publication | 2016-06-01 | Todd L. Lowary |